null

SMILES: CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(C[C@@H]1CCCN1C)C(=O)Cc1ccc(F)c(c1)C(F)(F)F)-c1ccccc1

InChI Key: InChIKey=DHCDUDRKAXLPJS-KCWPFWIISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371496 (CHEMBL403378) Show SMILES CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(C[C@@H]1CCCN1C)C(=O)Cc1ccc(F)c(c1)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C34H36F4N4O2/c1-4-44-28-15-13-26(14-16-28)42-22-31(25-9-6-5-7-10-25)39-33(42)23(2)41(21-27-11-8-18-40(27)3)32(43)20-24-12-17-30(35)29(19-24)34(36,37)38/h5-7,9-10,12-17,19,22-23,27H,4,8,11,18,20-21H2,1-3H3/t23-,27+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50371496 (CHEMBL403378) Show SMILES CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(C[C@@H]1CCCN1C)C(=O)Cc1ccc(F)c(c1)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C34H36F4N4O2/c1-4-44-28-15-13-26(14-16-28)42-22-31(25-9-6-5-7-10-25)39-33(42)23(2)41(21-27-11-8-18-40(27)3)32(43)20-24-12-17-30(35)29(19-24)34(36,37)38/h5-7,9-10,12-17,19,22-23,27H,4,8,11,18,20-21H2,1-3H3/t23-,27+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC				Bioorg Med Chem Lett 18: 608-13 (2008) Article DOI: 10.1016/j.bmcl.2007.11.072 BindingDB Entry DOI: 10.7270/Q2668F1D
					More data for this Ligand-Target Pair