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SMILES: C[C@H](CO)Nc1nc(SCc2ccccc2)nc2sc(N)nc12

InChI Key: InChIKey=IKXFUSDAMJSAQO-SECBINFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371781   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50371781
PNG
(CHEMBL258334)
Show SMILES C[C@H](CO)Nc1nc(SCc2ccccc2)nc2sc(N)nc12
Show InChI InChI=1S/C15H17N5OS2/c1-9(7-21)17-12-11-13(23-14(16)18-11)20-15(19-12)22-8-10-5-3-2-4-6-10/h2-6,9,21H,7-8H2,1H3,(H2,16,18)(H,17,19,20)/t9-/m1/s1
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n/an/a 850n/an/an/an/an/an/a



AstraZeneca R&D Charnwood

Curated by ChEMBL


Assay Description
Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 cells by SPA assay

Bioorg Med Chem Lett 18: 798-803 (2008)


BindingDB Entry DOI: 10.7270/Q28053GH
More data for this
Ligand-Target Pair