BDBM50371927 CHEMBL401736

SMILES: O=c1[nH]c2ccc(cc2c(-c2ccccc2)c1-c1c[nH]cn1)C#N

InChI Key: InChIKey=HJONPENWUASLHT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50371927 (CHEMBL401736) Show SMILES O=c1[nH]c2ccc(cc2c(-c2ccccc2)c1-c1c[nH]cn1)C#N Show InChI InChI=1S/C19H12N4O/c20-9-12-6-7-15-14(8-12)17(13-4-2-1-3-5-13)18(19(24)23-15)16-10-21-11-22-16/h1-8,10-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic macrophage colony-stimulating factor 1 receptor by fluorescence polarization				Bioorg Med Chem Lett 18: 2097-102 (2008) Article DOI: 10.1016/j.bmcl.2008.01.088 BindingDB Entry DOI: 10.7270/Q23779JH
					More data for this Ligand-Target Pair