BDBM50372065 CHEMBL272363

SMILES: CCOc1c2CN(C(=O)c2c(OCC)c2cccnc12)c1ccc(CS(=O)(=O)NC(=O)Cc2c(Cl)cccc2Cl)cc1C

InChI Key: InChIKey=BUEUZIUBSSDAOW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50372065 (CHEMBL272363) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2cccnc12)c1ccc(CS(=O)(=O)NC(=O)Cc2c(Cl)cccc2Cl)cc1C Show InChI InChI=1S/C31H29Cl2N3O6S/c1-4-41-29-20-8-7-13-34-28(20)30(42-5-2)22-16-36(31(38)27(22)29)25-12-11-19(14-18(25)3)17-43(39,40)35-26(37)15-21-23(32)9-6-10-24(21)33/h6-14H,4-5,15-17H2,1-3H3,(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2048-54 (2008) Article DOI: 10.1016/j.bmcl.2008.01.103 BindingDB Entry DOI: 10.7270/Q2J96770
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50372065 (CHEMBL272363) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2cccnc12)c1ccc(CS(=O)(=O)NC(=O)Cc2c(Cl)cccc2Cl)cc1C Show InChI InChI=1S/C31H29Cl2N3O6S/c1-4-41-29-20-8-7-13-34-28(20)30(42-5-2)22-16-36(31(38)27(22)29)25-12-11-19(14-18(25)3)17-43(39,40)35-26(37)15-21-23(32)9-6-10-24(21)33/h6-14H,4-5,15-17H2,1-3H3,(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells in presence of 10% human serum				Bioorg Med Chem Lett 18: 2048-54 (2008) Article DOI: 10.1016/j.bmcl.2008.01.103 BindingDB Entry DOI: 10.7270/Q2J96770
					More data for this Ligand-Target Pair