null

SMILES: OC1COc2cccc(Nc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2C1

InChI Key: InChIKey=WBQUTHJYYXHACE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50372579 (CHEMBL403425) Show SMILES OC1COc2cccc(Nc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2C1 |w:1.0| Show InChI InChI=1S/C20H16F3N3O2/c21-20(22,23)13-6-4-12(5-7-13)17-9-19(25-11-24-17)26-16-2-1-3-18-15(16)8-14(27)10-28-18/h1-7,9,11,14,27H,8,10H2,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilization				Bioorg Med Chem Lett 18: 1830-4 (2008) Article DOI: 10.1016/j.bmcl.2008.02.022 BindingDB Entry DOI: 10.7270/Q2FB53SJ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50372579 (CHEMBL403425) Show SMILES OC1COc2cccc(Nc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)c2C1 |w:1.0| Show InChI InChI=1S/C20H16F3N3O2/c21-20(22,23)13-6-4-12(5-7-13)17-9-19(25-11-24-17)26-16-2-1-3-18-15(16)8-14(27)10-28-18/h1-7,9,11,14,27H,8,10H2,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium mobilization				Bioorg Med Chem Lett 18: 1830-4 (2008) Article DOI: 10.1016/j.bmcl.2008.02.022 BindingDB Entry DOI: 10.7270/Q2FB53SJ
					More data for this Ligand-Target Pair