Found 4 hits for monomerid = 50372753 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50372753
(CHEMBL271845)Show SMILES O=C(Nc1ccc(cc1)C1CCCCC1)C1C(=O)C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H26N2O3/c27-21-15-20(18-9-5-2-6-10-18)26-24(29)22(21)23(28)25-19-13-11-17(12-14-19)16-7-3-1-4-8-16/h2,5-6,9-14,16,20,22H,1,3-4,7-8,15H2,(H,25,28)(H,26,29)/t20-,22?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human FPPS |
Bioorg Med Chem Lett 18: 1840-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.009 BindingDB Entry DOI: 10.7270/Q2CF9QZ5 |
More data for this Ligand-Target Pair | |
Undecaprenyl pyrophosphate synthase
(Streptococcus pneumoniae) | BDBM50372753
(CHEMBL271845)Show SMILES O=C(Nc1ccc(cc1)C1CCCCC1)C1C(=O)C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H26N2O3/c27-21-15-20(18-9-5-2-6-10-18)26-24(29)22(21)23(28)25-19-13-11-17(12-14-19)16-7-3-1-4-8-16/h2,5-6,9-14,16,20,22H,1,3-4,7-8,15H2,(H,25,28)(H,26,29)/t20-,22?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Streptococcus pneumoniae UPPS |
Bioorg Med Chem Lett 18: 1840-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.009 BindingDB Entry DOI: 10.7270/Q2CF9QZ5 |
More data for this Ligand-Target Pair | |
Undecaprenyl pyrophosphate synthase
(Streptococcus pneumoniae) | BDBM50372753
(CHEMBL271845)Show SMILES O=C(Nc1ccc(cc1)C1CCCCC1)C1C(=O)C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H26N2O3/c27-21-15-20(18-9-5-2-6-10-18)26-24(29)22(21)23(28)25-19-13-11-17(12-14-19)16-7-3-1-4-8-16/h2,5-6,9-14,16,20,22H,1,3-4,7-8,15H2,(H,25,28)(H,26,29)/t20-,22?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of Streptococcus pneumoniae UPPS |
Bioorg Med Chem Lett 18: 1840-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.009 BindingDB Entry DOI: 10.7270/Q2CF9QZ5 |
More data for this Ligand-Target Pair | |
Farnesyl diphosphate synthase
(Homo sapiens (Human)) | BDBM50372753
(CHEMBL271845)Show SMILES O=C(Nc1ccc(cc1)C1CCCCC1)C1C(=O)C[C@@H](NC1=O)c1ccccc1 Show InChI InChI=1S/C24H26N2O3/c27-21-15-20(18-9-5-2-6-10-18)26-24(29)22(21)23(28)25-19-13-11-17(12-14-19)16-7-3-1-4-8-16/h2,5-6,9-14,16,20,22H,1,3-4,7-8,15H2,(H,25,28)(H,26,29)/t20-,22?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Inhibition of human FPPS |
Bioorg Med Chem Lett 18: 1840-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.009 BindingDB Entry DOI: 10.7270/Q2CF9QZ5 |
More data for this Ligand-Target Pair | |