BDBM50372903 CHEMBL255821

SMILES: COc1cccc(C=C2SC(S)=NC2=O)c1OC

InChI Key: InChIKey=DCFBHAYQQWSRFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50372903 (CHEMBL255821) Show SMILES COc1cccc(C=C2SC(S)=NC2=O)c1OC |w:7.6,c:11| Show InChI InChI=1S/C12H11NO3S2/c1-15-8-5-3-4-7(10(8)16-2)6-9-11(14)13-12(17)18-9/h3-6H,1-2H3,(H,13,14,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Paisley Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 18: 2032-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.117 BindingDB Entry DOI: 10.7270/Q2BG2PVS
					More data for this Ligand-Target Pair