null

SMILES: CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(COCCN2CCCCC2)C1)cnn3-c1ccc(F)cc1

InChI Key: InChIKey=PVLDWGPAFHHLQK-UUWRZZSWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372919 (CHEMBL403966) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(COCCN2CCCCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C34H43FN4O3S/c1-33(2,3)27-7-13-31(14-8-27)43(40,41)38-18-15-28-21-32-26(23-36-39(32)30-11-9-29(35)10-12-30)22-34(28,24-38)25-42-20-19-37-16-5-4-6-17-37/h7-14,21,23H,4-6,15-20,22,24-25H2,1-3H3/t34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372919 (CHEMBL403966) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(COCCN2CCCCC2)C1)cnn3-c1ccc(F)cc1 |t:17| Show InChI InChI=1S/C34H43FN4O3S/c1-33(2,3)27-7-13-31(14-8-27)43(40,41)38-18-15-28-21-32-26(23-36-39(32)30-11-9-29(35)10-12-30)22-34(28,24-38)25-42-20-19-37-16-5-4-6-17-37/h7-14,21,23H,4-6,15-20,22,24-25H2,1-3H3/t34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair