null

SMILES: OC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=ZSOYCCGDQFNMCS-HSZRJFAPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372973 (CHEMBL271054) Show SMILES OC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 |c:8| Show InChI InChI=1S/C23H21F2N3O3S/c24-18-1-5-20(6-2-18)28-22-11-17-9-10-27(14-23(17,15-29)12-16(22)13-26-28)32(30,31)21-7-3-19(25)4-8-21/h1-8,11,13,29H,9-10,12,14-15H2/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant GR				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50372973 (CHEMBL271054) Show SMILES OC[C@@]12CN(CCC1=Cc1c(C2)cnn1-c1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 |c:8| Show InChI InChI=1S/C23H21F2N3O3S/c24-18-1-5-20(6-2-18)28-22-11-17-9-10-27(14-23(17,15-29)12-16(22)13-26-28)32(30,31)21-7-3-19(25)4-8-21/h1-8,11,13,29H,9-10,12,14-15H2/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression				Bioorg Med Chem Lett 18: 1312-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.027 BindingDB Entry DOI: 10.7270/Q22Z16CP
					More data for this Ligand-Target Pair