BDBM50373166 CHEMBL259819

SMILES: CCOC(=O)C1C(=O)C(SC1=Nc1ccccc1)=Cc1cccc(O)c1

InChI Key: InChIKey=IDSZGGCDTQUUCU-UHFFFAOYSA-N

Data: 1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Homo sapiens (Human))	BDBM50373166 (CHEMBL259819) Show SMILES CCOC(=O)C1C(=O)C(SC1=Nc1ccccc1)=Cc1cccc(O)c1 |w:18.20,11.12| Show InChI InChI=1S/C20H17NO4S/c1-2-25-20(24)17-18(23)16(12-13-7-6-10-15(22)11-13)26-19(17)21-14-8-4-3-5-9-14/h3-12,17,22H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
Lerner Research Institute Curated by ChEMBL					Assay Description Displacement of 5'-phosphorylated, 2',5'-oligoadenylate from human recombinant RNase L assessed as decrease in resonance by surface plasma resonance				Proc Natl Acad Sci USA 104: 9585-90 (2007) Article DOI: 10.1073/pnas.0700590104 BindingDB Entry DOI: 10.7270/Q2G161PZ
					More data for this Ligand-Target Pair
RNase L (Homo sapiens (Human))	BDBM50373166 (CHEMBL259819) Show SMILES CCOC(=O)C1C(=O)C(SC1=Nc1ccccc1)=Cc1cccc(O)c1 |w:18.20,11.12| Show InChI InChI=1S/C20H17NO4S/c1-2-25-20(24)17-18(23)16(12-13-7-6-10-15(22)11-13)26-19(17)21-14-8-4-3-5-9-14/h3-12,17,22H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a
Lerner Research Institute Curated by ChEMBL					Assay Description Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probe				Proc Natl Acad Sci USA 104: 9585-90 (2007) Article DOI: 10.1073/pnas.0700590104 BindingDB Entry DOI: 10.7270/Q2G161PZ
					More data for this Ligand-Target Pair