BDBM50373201 CHEMBL261186

SMILES: COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(NS(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=DDOZMWFAUFLURA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50373201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50373201 (CHEMBL261186) Show SMILES COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C30H23BrN2O5S/c1-38-30(35)28-27(21-8-4-2-5-9-21)26-18-22(31)14-17-25(26)29(34)33(28)19-20-12-15-23(16-13-20)32-39(36,37)24-10-6-3-7-11-24/h2-18,32H,19H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human JNK1 by radiometric assay				Bioorg Med Chem 16: 4715-32 (2008) Article DOI: 10.1016/j.bmc.2008.02.027 BindingDB Entry DOI: 10.7270/Q2JS9R8M
					More data for this Ligand-Target Pair