Found 3 hits for monomerid = 50373281 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50373281
(CHEMBL402441)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N(CC#C)CC#C)c1ccc2OCCOc2c1 Show InChI InChI=1S/C19H20N2O3/c1-3-7-21(8-4-2)18(22)19(12-15(19)13-20)14-5-6-16-17(11-14)24-10-9-23-16/h1-2,5-6,11,15H,7-10,12-13,20H2/t15-,19+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 18: 3328-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50373281
(CHEMBL402441)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N(CC#C)CC#C)c1ccc2OCCOc2c1 Show InChI InChI=1S/C19H20N2O3/c1-3-7-21(8-4-2)18(22)19(12-15(19)13-20)14-5-6-16-17(11-14)24-10-9-23-16/h1-2,5-6,11,15H,7-10,12-13,20H2/t15-,19+/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human DAT |
Bioorg Med Chem Lett 18: 3328-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50373281
(CHEMBL402441)Show SMILES NC[C@@H]1C[C@@]1(C(=O)N(CC#C)CC#C)c1ccc2OCCOc2c1 Show InChI InChI=1S/C19H20N2O3/c1-3-7-21(8-4-2)18(22)19(12-15(19)13-20)14-5-6-16-17(11-14)24-10-9-23-16/h1-2,5-6,11,15H,7-10,12-13,20H2/t15-,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Bioscience, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human NET |
Bioorg Med Chem Lett 18: 3328-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK |
More data for this Ligand-Target Pair | |