null

SMILES: Fc1cc2nc(SCc3c(Cl)cccc3Cl)[nH]c2cc1N1CCNCC1

InChI Key: InChIKey=LJDRWQFSRLXSNI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50373374 (CHEMBL260822) Show SMILES Fc1cc2nc(SCc3c(Cl)cccc3Cl)[nH]c2cc1N1CCNCC1 Show InChI InChI=1S/C18H17Cl2FN4S/c19-12-2-1-3-13(20)11(12)10-26-18-23-15-8-14(21)17(9-16(15)24-18)25-6-4-22-5-7-25/h1-3,8-9,22H,4-7,10H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC from human ORL1 receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 18: 3278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.04.054 BindingDB Entry DOI: 10.7270/Q2HT2Q57
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50373374 (CHEMBL260822) Show SMILES Fc1cc2nc(SCc3c(Cl)cccc3Cl)[nH]c2cc1N1CCNCC1 Show InChI InChI=1S/C18H17Cl2FN4S/c19-12-2-1-3-13(20)11(12)10-26-18-23-15-8-14(21)17(9-16(15)24-18)25-6-4-22-5-7-25/h1-3,8-9,22H,4-7,10H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human ORL1 receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assay				Bioorg Med Chem Lett 18: 3278-81 (2008) Article DOI: 10.1016/j.bmcl.2008.04.054 BindingDB Entry DOI: 10.7270/Q2HT2Q57
					More data for this Ligand-Target Pair