BDBM50373504 CHEMBL272515

SMILES: CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)c(Cl)c1)C(C)C

InChI Key: InChIKey=KMWZPGLREBIDRH-HEHLMWRFSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50373504 (CHEMBL272515) Show SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)c(Cl)c1)C(C)C Show InChI InChI=1S/C33H46ClF2N5O2/c1-21(2)31(37-30(42)12-13-38(5)6)24-8-7-9-29(36)32(24)39-14-16-40(17-15-39)33(43)26-20-41(22(3)4)19-25(26)23-10-11-28(35)27(34)18-23/h7-11,18,21-22,25-26,31H,12-17,19-20H2,1-6H3,(H,37,42)/t25-,26+,31-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 129-36 (2008) Article DOI: 10.1016/j.bmcl.2007.10.115 BindingDB Entry DOI: 10.7270/Q2MK6DR5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50373504 (CHEMBL272515) Show SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)c(Cl)c1)C(C)C Show InChI InChI=1S/C33H46ClF2N5O2/c1-21(2)31(37-30(42)12-13-38(5)6)24-8-7-9-29(36)32(24)39-14-16-40(17-15-39)33(43)26-20-41(22(3)4)19-25(26)23-10-11-28(35)27(34)18-23/h7-11,18,21-22,25-26,31H,12-17,19-20H2,1-6H3,(H,37,42)/t25-,26+,31-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor expressed in CHO cells assessed as accumulation of cAMP production				Bioorg Med Chem Lett 18: 129-36 (2008) Article DOI: 10.1016/j.bmcl.2007.10.115 BindingDB Entry DOI: 10.7270/Q2MK6DR5
					More data for this Ligand-Target Pair