BindingDB PrimarySearch_ki

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null

SMILES: COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF

InChI Key: InChIKey=FKHJOYFNYFVDRF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50373708
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50373708 (CHEMBL256492) Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinic of Nuclear Medicine Curated by ChEMBL					Assay Description Binding affinity to human dopamine D2 long receptor				Bioorg Med Chem Lett 18: 983-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.026 BindingDB Entry DOI: 10.7270/Q2B56KMT
Clinic of Nuclear Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50373708 (CHEMBL256492) Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinic of Nuclear Medicine Curated by ChEMBL					Assay Description Binding affinity to human D3 receptor				Bioorg Med Chem Lett 18: 983-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.026 BindingDB Entry DOI: 10.7270/Q2B56KMT
Clinic of Nuclear Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (PIG)	BDBM50373708 (CHEMBL256492) Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinic of Nuclear Medicine Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor				Bioorg Med Chem Lett 18: 983-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.026 BindingDB Entry DOI: 10.7270/Q2B56KMT
Clinic of Nuclear Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM50373708 (CHEMBL256492) Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinic of Nuclear Medicine Curated by ChEMBL					Assay Description Binding affinity to pig cortical membrane dopamine D1 receptor				Bioorg Med Chem Lett 18: 983-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.026 BindingDB Entry DOI: 10.7270/Q2B56KMT
Clinic of Nuclear Medicine Curated by ChEMBL					More data for this Ligand-Target Pair