null

SMILES: Cc1c(CCO)sc[n+]1Cc1cc(I)cnc1N

InChI Key: InChIKey=RZRRPQWNCOERGA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transketolase (Homo sapiens (Human))	BDBM50373721 (CHEMBL270384) Show SMILES Cc1c(CCO)sc[n+]1Cc1cc(I)cnc1N Show InChI InChI=1S/C12H15IN3OS/c1-8-11(2-3-17)18-7-16(8)6-9-4-10(13)5-15-12(9)14/h4-5,7,17H,2-3,6H2,1H3,(H2,14,15)/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Array BioPharma Inc. Curated by ChEMBL					Assay Description Inhibition of human transketolase in HCT116 cells				Bioorg Med Chem Lett 18: 2206-10 (2008) Article DOI: 10.1016/j.bmcl.2007.11.101 BindingDB Entry DOI: 10.7270/Q26D5TVN
					More data for this Ligand-Target Pair
Transketolase (Homo sapiens (Human))	BDBM50373721 (CHEMBL270384) Show SMILES Cc1c(CCO)sc[n+]1Cc1cc(I)cnc1N Show InChI InChI=1S/C12H15IN3OS/c1-8-11(2-3-17)18-7-16(8)6-9-4-10(13)5-15-12(9)14/h4-5,7,17H,2-3,6H2,1H3,(H2,14,15)/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. Curated by ChEMBL					Assay Description Inhibition of transketolase by TPPK/apo-TK coupled assay				Bioorg Med Chem Lett 18: 2206-10 (2008) Article DOI: 10.1016/j.bmcl.2007.11.101 BindingDB Entry DOI: 10.7270/Q26D5TVN
					More data for this Ligand-Target Pair