BDBM50373790 CHEMBL445069

SMILES: Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)-c1cccc(F)c1F

InChI Key: InChIKey=OJFXKQROKKJNQP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50373790 (CHEMBL445069) Show SMILES Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)-c1cccc(F)c1F Show InChI InChI=1S/C24H22F2N6O3/c1-30-13-14(16-4-2-5-17(25)20(16)26)12-18(22(30)33)28-23(34)31-10-7-15(8-11-31)32-19-6-3-9-27-21(19)29-24(32)35/h2-6,9,12-13,15H,7-8,10-11H2,1H3,(H,28,34)(H,27,29,35)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human recombinant CL receptor /RAMP1				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50373790 (CHEMBL445069) Show SMILES Cn1cc(cc(NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)c1=O)-c1cccc(F)c1F Show InChI InChI=1S/C24H22F2N6O3/c1-30-13-14(16-4-2-5-17(25)20(16)26)12-18(22(30)33)28-23(34)31-10-7-15(8-11-31)32-19-6-3-9-27-21(19)29-24(32)35/h2-6,9,12-13,15H,7-8,10-11H2,1H3,(H,28,34)(H,27,29,35)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	567	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assay				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair