BDBM50373881 CHEMBL257285
SMILES: Cc1c(Cc2cncnc2N)csc1CCO
InChI Key: InChIKey=MEZQUELVNWOHDN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50373881 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Transketolase
(Homo sapiens (Human)) | BDBM50373881
(CHEMBL257285)Show InChI InChI=1S/C12H15N3OS/c1-8-10(6-17-11(8)2-3-16)4-9-5-14-7-15-12(9)13/h5-7,16H,2-4H2,1H3,(H2,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a |
Array BioPharma Inc.
Curated by ChEMBL
| Assay Description Inhibition of transketolase in human HCT116 cells |
Bioorg Med Chem Lett 18: 509-12 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.098 BindingDB Entry DOI: 10.7270/Q2WW7JJ3 |
More data for this Ligand-Target Pair | |
Transketolase
(Homo sapiens (Human)) | BDBM50373881
(CHEMBL257285)Show InChI InChI=1S/C12H15N3OS/c1-8-10(6-17-11(8)2-3-16)4-9-5-14-7-15-12(9)13/h5-7,16H,2-4H2,1H3,(H2,13,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc.
Curated by ChEMBL
| Assay Description Inhibition of apo-transketolase |
Bioorg Med Chem Lett 18: 509-12 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.098 BindingDB Entry DOI: 10.7270/Q2WW7JJ3 |
More data for this Ligand-Target Pair | |