BDBM50373883 CHEMBL255345
SMILES: Cc1c(Cc2cnc(N)nc2N)csc1CCO
InChI Key: InChIKey=CJBMRDRJZUVESD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50373883 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Transketolase
(Homo sapiens (Human)) | BDBM50373883
(CHEMBL255345)Show InChI InChI=1S/C12H16N4OS/c1-7-9(6-18-10(7)2-3-17)4-8-5-15-12(14)16-11(8)13/h5-6,17H,2-4H2,1H3,(H4,13,14,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a |
Array BioPharma Inc.
Curated by ChEMBL
| Assay Description Inhibition of transketolase in human HCT116 cells |
Bioorg Med Chem Lett 18: 509-12 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.098 BindingDB Entry DOI: 10.7270/Q2WW7JJ3 |
More data for this Ligand-Target Pair | |
Transketolase
(Homo sapiens (Human)) | BDBM50373883
(CHEMBL255345)Show InChI InChI=1S/C12H16N4OS/c1-7-9(6-18-10(7)2-3-17)4-8-5-15-12(14)16-11(8)13/h5-6,17H,2-4H2,1H3,(H4,13,14,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a |
Array BioPharma Inc.
Curated by ChEMBL
| Assay Description Inhibition of apo-transketolase |
Bioorg Med Chem Lett 18: 509-12 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.098 BindingDB Entry DOI: 10.7270/Q2WW7JJ3 |
More data for this Ligand-Target Pair | |