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SMILES: Nc1nc2ccc(cc2n1-c1ccccc1)-c1[nH]c(nc1-c1ccccc1)-c1c(F)cccc1F

InChI Key: InChIKey=FBAOMSQXJXDFPJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50373969   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50373969
PNG
(CHEMBL404547)
Show SMILES Nc1nc2ccc(cc2n1-c1ccccc1)-c1[nH]c(nc1-c1ccccc1)-c1c(F)cccc1F
Show InChI InChI=1S/C28H19F2N5/c29-20-12-7-13-21(30)24(20)27-33-25(17-8-3-1-4-9-17)26(34-27)18-14-15-22-23(16-18)35(28(31)32-22)19-10-5-2-6-11-19/h1-16H,(H2,31,32)(H,33,34)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Eli Lilly and Co.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant p38alpha

Bioorg Med Chem Lett 18: 179-83 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.106
BindingDB Entry DOI: 10.7270/Q2R78G31
More data for this
Ligand-Target Pair