null

SMILES: Fc1cccc(F)c1-c1nc(c([nH]1)-c1ccccc1)-c1ccc2nc[nH]c2c1

InChI Key: InChIKey=UVWRWJVEPPBDPX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50373976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Mus musculus (mouse))	BDBM50373976 (CHEMBL272535) Show SMILES Fc1cccc(F)c1-c1nc(c([nH]1)-c1ccccc1)-c1ccc2nc[nH]c2c1 Show InChI InChI=1S/C22H14F2N4/c23-15-7-4-8-16(24)19(15)22-27-20(13-5-2-1-3-6-13)21(28-22)14-9-10-17-18(11-14)26-12-25-17/h1-12H,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	766	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Co. Curated by ChEMBL					Assay Description Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISA				Bioorg Med Chem Lett 18: 179-83 (2008) Article DOI: 10.1016/j.bmcl.2007.10.106 BindingDB Entry DOI: 10.7270/Q2R78G31
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50373976 (CHEMBL272535) Show SMILES Fc1cccc(F)c1-c1nc(c([nH]1)-c1ccccc1)-c1ccc2nc[nH]c2c1 Show InChI InChI=1S/C22H14F2N4/c23-15-7-4-8-16(24)19(15)22-27-20(13-5-2-1-3-6-13)21(28-22)14-9-10-17-18(11-14)26-12-25-17/h1-12H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88.4	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha				Bioorg Med Chem Lett 18: 179-83 (2008) Article DOI: 10.1016/j.bmcl.2007.10.106 BindingDB Entry DOI: 10.7270/Q2R78G31
					More data for this Ligand-Target Pair