BDBM50374013 CHEMBL438736

SMILES: Oc1ccc(cc1NC(=O)C\C=C\c1ccccc1)-c1ccccc1

InChI Key: InChIKey=WFKLWFUAWPVHBM-JXMROGBWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374013 (CHEMBL438736) Show SMILES Oc1ccc(cc1NC(=O)C\C=C\c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H19NO2/c24-21-15-14-19(18-11-5-2-6-12-18)16-20(21)23-22(25)13-7-10-17-8-3-1-4-9-17/h1-12,14-16,24H,13H2,(H,23,25)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair