BDBM50374041 CHEMBL257953

SMILES: COC(=O)CCc1ccc(cc1)-c1ccc(N)c(NC(=O)c2cccnc2)c1

InChI Key: InChIKey=QARFBGSLEQTMCU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50374041 (CHEMBL257953) Show SMILES COC(=O)CCc1ccc(cc1)-c1ccc(N)c(NC(=O)c2cccnc2)c1 Show InChI InChI=1S/C22H21N3O3/c1-28-21(26)11-6-15-4-7-16(8-5-15)17-9-10-19(23)20(13-17)25-22(27)18-3-2-12-24-14-18/h2-5,7-10,12-14H,6,11,23H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 18: 973-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.031 BindingDB Entry DOI: 10.7270/Q2765G5S
					More data for this Ligand-Target Pair