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BDBM50374093 CHEMBL270241

SMILES: O=C1CCCN1CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12

InChI Key: InChIKey=ZBSRSMRKEMXADB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50374093
PNG
(CHEMBL270241)
Show SMILES O=C1CCCN1CCc1ccc(cc1)C1=CCC2CN(Cc3ccccc3)CC12 |w:17.18,28.30,t:16|
Show InChI InChI=1S/C26H30N2O/c29-26-7-4-15-28(26)16-14-20-8-10-22(11-9-20)24-13-12-23-18-27(19-25(23)24)17-21-5-2-1-3-6-21/h1-3,5-6,8-11,13,23,25H,4,7,12,14-19H2
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Similars
Article
PubMed
 310n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex

Bioorg Med Chem Lett 18: 1490-4 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.059
BindingDB Entry DOI: 10.7270/Q2Q81DZS
More data for this
Ligand-Target Pair