BDBM50374115 CHEMBL270691

SMILES: Clc1ccc2c(c1)N(Cc1ccc3ccccc3c1)C(=O)C(Cc1ccccc1)NC2=O

InChI Key: InChIKey=BZDRLTZGNVDUFJ-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50374115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Mus musculus)	BDBM50374115 (CHEMBL270691) Show SMILES Clc1ccc2c(c1)N(Cc1ccc3ccccc3c1)C(=O)C(Cc1ccccc1)NC2=O |w:21.24| Show InChI InChI=1S/C27H21ClN2O2/c28-22-12-13-23-25(16-22)30(17-19-10-11-20-8-4-5-9-21(20)14-19)27(32)24(29-26(23)31)15-18-6-2-1-3-7-18/h1-14,16,24H,15,17H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay				J Med Chem 51: 1423-31 (2008) Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Mus musculus (Mouse))	BDBM50374115 (CHEMBL270691) Show SMILES Clc1ccc2c(c1)N(Cc1ccc3ccccc3c1)C(=O)C(Cc1ccccc1)NC2=O |w:21.24| Show InChI InChI=1S/C27H21ClN2O2/c28-22-12-13-23-25(16-22)30(17-19-10-11-20-8-4-5-9-21(20)14-19)27(32)24(29-26(23)31)15-18-6-2-1-3-7-18/h1-14,16,24H,15,17H2,(H,29,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.35E+3	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity at mouse MC5R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay				J Med Chem 51: 1423-31 (2008) Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61
					More data for this Ligand-Target Pair
Melanocortin receptor 1 (Mus musculus)	BDBM50374115 (CHEMBL270691) Show SMILES Clc1ccc2c(c1)N(Cc1ccc3ccccc3c1)C(=O)C(Cc1ccccc1)NC2=O |w:21.24| Show InChI InChI=1S/C27H21ClN2O2/c28-22-12-13-23-25(16-22)30(17-19-10-11-20-8-4-5-9-21(20)14-19)27(32)24(29-26(23)31)15-18-6-2-1-3-7-18/h1-14,16,24H,15,17H2,(H,29,31)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Agonist activity at mouse MC1R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay				J Med Chem 51: 1423-31 (2008) Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61
					More data for this Ligand-Target Pair