BDBM50374189 CHEMBL441897

SMILES: CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34

InChI Key: InChIKey=IYKCWOIZNVHUMI-GUYCJALGSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50374189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCdelta C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCtheta C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	223	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCeta C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCepsilon C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha C1A domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCbeta C1A domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCgamma C1A domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCgamma C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCalpha C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50374189 (CHEMBL441897) Show SMILES CC(C)[C@@H]1N(C)c2ccc3c(C)nn4cc(C[C@@H](CO)NC1=O)c2c34 Show InChI InChI=1S/C19H24N4O2/c1-10(2)17-19(25)20-13(9-24)7-12-8-23-18-14(11(3)21-23)5-6-15(16(12)18)22(17)4/h5-6,8,10,13,17,24H,7,9H2,1-4H3,(H,20,25)/t13-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from PKCbeta C1B domain				Bioorg Med Chem 16: 650-7 (2008) Article DOI: 10.1016/j.bmc.2007.10.045 BindingDB Entry DOI: 10.7270/Q2XS5W85
					More data for this Ligand-Target Pair