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BDBM50374875 CHEMBL269955

SMILES: Clc1ccc2cc(sc2n1)S(=O)(=O)NC1CCCN(C1=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=XEOZTCMTXQCNRS-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50374875   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50374875
PNG
(CHEMBL269955)
Show SMILES Clc1ccc2cc(sc2n1)S(=O)(=O)NC1CCCN(C1=O)c1ccc(cc1)-n1ccccc1=O |w:14.15|
Show InChI InChI=1S/C23H19ClN4O4S2/c24-19-11-6-15-14-21(33-22(15)25-19)34(31,32)26-18-4-3-13-28(23(18)30)17-9-7-16(8-10-17)27-12-2-1-5-20(27)29/h1-2,5-12,14,18,26H,3-4,13H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
0.0500n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 18: 2428-33 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.054
BindingDB Entry DOI: 10.7270/Q2RX9CZ8
More data for this
Ligand-Target Pair