BDBM50374943 CHEMBL429757

SMILES: [#6]-[#6]S(=O)(=O)c1ccc(-c2noc(n2)-[#6](-[#6])-[#6@H](-[#7])-[#6](\F)=[#6]-2/[#6]-[#6]-[#6]-[#6]-2)c(Cl)c1

InChI Key: InChIKey=HTRJNCXDNJEXTE-KLLZUTDZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50374943 (CHEMBL429757) Show SMILES [#6]-[#6]S(=O)(=O)c1ccc(-c2noc(n2)-[#6](-[#6])-[#6@H](-[#7])-[#6](\F)=[#6]-2/[#6]-[#6]-[#6]-[#6]-2)c(Cl)c1 |r| Show InChI InChI=1S/C19H23ClFN3O3S/c1-3-28(25,26)13-8-9-14(15(20)10-13)18-23-19(27-24-18)11(2)17(22)16(21)12-6-4-5-7-12/h8-11,17H,3-7,22H2,1-2H3/t11?,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant QPP expressed in baculovirus system				Bioorg Med Chem Lett 18: 2409-13 (2008) Article DOI: 10.1016/j.bmcl.2008.02.050 BindingDB Entry DOI: 10.7270/Q2HD7WJ0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50374943 (CHEMBL429757) Show SMILES [#6]-[#6]S(=O)(=O)c1ccc(-c2noc(n2)-[#6](-[#6])-[#6@H](-[#7])-[#6](\F)=[#6]-2/[#6]-[#6]-[#6]-[#6]-2)c(Cl)c1 |r| Show InChI InChI=1S/C19H23ClFN3O3S/c1-3-28(25,26)13-8-9-14(15(20)10-13)18-23-19(27-24-18)11(2)17(22)16(21)12-6-4-5-7-12/h8-11,17H,3-7,22H2,1-2H3/t11?,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 expressed in insect cell				Bioorg Med Chem Lett 18: 2409-13 (2008) Article DOI: 10.1016/j.bmcl.2008.02.050 BindingDB Entry DOI: 10.7270/Q2HD7WJ0
					More data for this Ligand-Target Pair