BDBM50375045 CHEMBL261775

SMILES: [O-][N+](=O)c1cnc2cccc(N3CCN(CC3)C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)n12

InChI Key: InChIKey=IQPDNNPAWCSXOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50375045 (CHEMBL261775) Show SMILES [O-][N+](=O)c1cnc2cccc(N3CCN(CC3)C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)n12 Show InChI InChI=1S/C24H22ClN5O5S/c25-19-6-4-18-15-20(7-5-17(18)14-19)36(34,35)13-8-24(31)28-11-9-27(10-12-28)22-3-1-2-21-26-16-23(29(21)22)30(32)33/h1-7,14-16H,8-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 16: 3125-40 (2008) Article DOI: 10.1016/j.bmc.2007.12.024 BindingDB Entry DOI: 10.7270/Q2VQ33J5
					More data for this Ligand-Target Pair