BDBM50375132 CHEMBL271081

SMILES: CCOC(=O)CCn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N

InChI Key: InChIKey=BLKSDTGJDRGAEP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50375132 (CHEMBL271081) Show SMILES CCOC(=O)CCn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N Show InChI InChI=1S/C20H20ClN3O3/c1-2-27-19(26)11-12-23-16-5-3-4-6-17(16)24(20(23)22)13-18(25)14-7-9-15(21)10-8-14/h3-10,22H,2,11-13H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPR				Bioorg Med Chem Lett 18: 2414-9 (2008) Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC
					More data for this Ligand-Target Pair
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50375132 (CHEMBL271081) Show SMILES CCOC(=O)CCn1c2ccccc2n(CC(=O)c2ccc(Cl)cc2)c1=N Show InChI InChI=1S/C20H20ClN3O3/c1-2-27-19(26)11-12-23-16-5-3-4-6-17(16)24(20(23)22)13-18(25)14-7-9-15(21)10-8-14/h3-10,22H,2,11-13H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membrane				Bioorg Med Chem Lett 18: 2414-9 (2008) Article DOI: 10.1016/j.bmcl.2008.02.049 BindingDB Entry DOI: 10.7270/Q2BP03NC
					More data for this Ligand-Target Pair