BDBM50375167 CHEMBL270356
SMILES: [#6]-[#8]-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)cc1
InChI Key: InChIKey=IWKTUKNFSHWMNP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human)) | BDBM50375167 (CHEMBL270356) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University Curated by ChEMBL | Assay Description Inhibition of human methionine aminopeptidase 1 | Bioorg Med Chem Lett 18: 2373-6 (2008) Article DOI: 10.1016/j.bmcl.2008.02.066 BindingDB Entry DOI: 10.7270/Q2348M7J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50375167 (CHEMBL270356) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China National Analytical Center (Guangzhou) Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate assessed as formation of DOPAchrome preincubated for 10 mins followe... | Bioorg Med Chem 22: 3279-84 (2014) Article DOI: 10.1016/j.bmc.2014.04.060 BindingDB Entry DOI: 10.7270/Q2FB55WQ | |||||||||||
More data for this Ligand-Target Pair |