BDBM50375369 CHEMBL260024

SMILES: COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(C)nc3c2C(N)=O)cc(OC)c1

InChI Key: InChIKey=LGJSOGNULIDMSX-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50375369 (CHEMBL260024) Show SMILES COc1cc(Nc2nn3c(N[C@@H](CO)C(C)C)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C21H28N6O4/c1-11(2)16(10-28)25-17-6-12(3)23-21-18(19(22)29)20(26-27(17)21)24-13-7-14(30-4)9-15(8-13)31-5/h6-9,11,16,25,28H,10H2,1-5H3,(H2,22,29)(H,24,26)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	432	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human cSrc				Bioorg Med Chem 16: 909-21 (2008) Article DOI: 10.1016/j.bmc.2007.10.068 BindingDB Entry DOI: 10.7270/Q2CF9R01
					More data for this Ligand-Target Pair