BDBM50375723 CHEMBL257063

SMILES: COc1ccc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1

InChI Key: InChIKey=VMFLXCOSNOBSCD-MRXNPFEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50375723 (CHEMBL257063) Show SMILES COc1ccc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1 Show InChI InChI=1S/C22H25F3N4O3/c1-32-17-5-2-14(3-6-17)12-29-9-8-16(13-29)28-20(30)11-27-21(31)18-10-15(22(23,24)25)4-7-19(18)26/h2-7,10,16H,8-9,11-13,26H2,1H3,(H,27,31)(H,28,30)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Deltagen Research Laboratories (Former CombiChem, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxis				Bioorg Med Chem Lett 18: 1869-73 (2008) Article DOI: 10.1016/j.bmcl.2008.02.015 BindingDB Entry DOI: 10.7270/Q2W95B2Q
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50375723 (CHEMBL257063) Show SMILES COc1ccc(CN2CC[C@H](C2)NC(=O)CNC(=O)c2cc(ccc2N)C(F)(F)F)cc1 Show InChI InChI=1S/C22H25F3N4O3/c1-32-17-5-2-14(3-6-17)12-29-9-8-16(13-29)28-20(30)11-27-21(31)18-10-15(22(23,24)25)4-7-19(18)26/h2-7,10,16H,8-9,11-13,26H2,1H3,(H,27,31)(H,28,30)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Deltagen Research Laboratories (Former CombiChem, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from human CCR2b in THP1 cells				Bioorg Med Chem Lett 18: 1869-73 (2008) Article DOI: 10.1016/j.bmcl.2008.02.015 BindingDB Entry DOI: 10.7270/Q2W95B2Q
					More data for this Ligand-Target Pair