Found 5 hits for monomerid = 50376004 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376004
(CHEMBL271189)Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of KDR |
J Med Chem 51: 1668-80 (2008)
Article DOI: 10.1021/jm701098w
BindingDB Entry DOI: 10.7270/Q2F47Q0C |
More data for this
Ligand-Target Pair | |
Angiopoietin-1 receptor
(Homo sapiens (Human)) | BDBM50376004
(CHEMBL271189)Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Tie2 |
J Med Chem 51: 1668-80 (2008)
Article DOI: 10.1021/jm701098w
BindingDB Entry DOI: 10.7270/Q2F47Q0C |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50376004
(CHEMBL271189)Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.17 | n/a | n/a | n/a | n/a | n/a | n/a |
Lanzhou University
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 after 60 mins |
J Mol Graph Model 27: 642-54 (2008)
Article DOI: 10.1016/j.jmgm.2008.10.006
BindingDB Entry DOI: 10.7270/Q2C24XNX |
More data for this
Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50376004
(CHEMBL271189)Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Aurora A |
J Med Chem 51: 1668-80 (2008)
Article DOI: 10.1021/jm701098w
BindingDB Entry DOI: 10.7270/Q2F47Q0C |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50376004
(CHEMBL271189)Show SMILES COCCCNC(=O)c1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C26H26N2O5/c1-30-13-5-11-28-26(29)20-7-4-6-17-14-18(8-9-19(17)20)33-23-10-12-27-22-16-25(32-3)24(31-2)15-21(22)23/h4,6-10,12,14-16H,5,11,13H2,1-3H3,(H,28,29) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Lck |
J Med Chem 51: 1668-80 (2008)
Article DOI: 10.1021/jm701098w
BindingDB Entry DOI: 10.7270/Q2F47Q0C |
More data for this
Ligand-Target Pair | |
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