BDBM50376187 CHEMBL260365

SMILES: CCCCCCCCc1ccc(OCC(=O)COc2ccc3n(C)c(cc3c2)C(O)=O)cc1

InChI Key: InChIKey=MLUSWPORPIZRAF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50376187 (CHEMBL260365) Show SMILES CCCCCCCCc1ccc(OCC(=O)COc2ccc3n(C)c(cc3c2)C(O)=O)cc1 Show InChI InChI=1S/C27H33NO5/c1-3-4-5-6-7-8-9-20-10-12-23(13-11-20)32-18-22(29)19-33-24-14-15-25-21(16-24)17-26(27(30)31)28(25)2/h10-17H,3-9,18-19H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of human platelet cPLA2-alpha activity				Bioorg Med Chem 16: 3489-500 (2008) Article DOI: 10.1016/j.bmc.2008.02.019 BindingDB Entry DOI: 10.7270/Q2W66MN0
					More data for this Ligand-Target Pair
cPLA2 C2 (Homo sapiens (Human))	BDBM50376187 (CHEMBL260365) Show SMILES CCCCCCCCc1ccc(OCC(=O)COc2ccc3n(C)c(cc3c2)C(O)=O)cc1 Show InChI InChI=1S/C27H33NO5/c1-3-4-5-6-7-8-9-20-10-12-23(13-11-20)32-18-22(29)19-33-24-14-15-25-21(16-24)17-26(27(30)31)28(25)2/h10-17H,3-9,18-19H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 mins				Bioorg Med Chem 16: 3489-500 (2008) Article DOI: 10.1016/j.bmc.2008.02.019 BindingDB Entry DOI: 10.7270/Q2W66MN0
					More data for this Ligand-Target Pair