null

SMILES: NC(CC1c2ccccc2Oc2ccccc12)(C1CC1(F)C(O)=O)C(O)=O

InChI Key: InChIKey=HVYIQBGXHPRJMO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50376406 (CHEMBL259435) Show SMILES NC(CC1c2ccccc2Oc2ccccc12)(C1CC1(F)C(O)=O)C(O)=O |w:17.20,19.23,1.0| Show InChI InChI=1S/C20H18FNO5/c21-19(17(23)24)10-16(19)20(22,18(25)26)9-13-11-5-1-3-7-14(11)27-15-8-4-2-6-12(13)15/h1-8,13,16H,9-10,22H2,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cells				Bioorg Med Chem 16: 4359-66 (2008) Article DOI: 10.1016/j.bmc.2008.02.066 BindingDB Entry DOI: 10.7270/Q2PG1SMM
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50376406 (CHEMBL259435) Show SMILES NC(CC1c2ccccc2Oc2ccccc12)(C1CC1(F)C(O)=O)C(O)=O |w:17.20,19.23,1.0| Show InChI InChI=1S/C20H18FNO5/c21-19(17(23)24)10-16(19)20(22,18(25)26)9-13-11-5-1-3-7-14(11)27-15-8-4-2-6-12(13)15/h1-8,13,16H,9-10,22H2,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.45	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cells				Bioorg Med Chem 16: 4359-66 (2008) Article DOI: 10.1016/j.bmc.2008.02.066 BindingDB Entry DOI: 10.7270/Q2PG1SMM
					More data for this Ligand-Target Pair