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SMILES: CCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cccc(c4)-n4cccn4)ccc3C)c2c1C

InChI Key: InChIKey=VUXICMXZQBHLEC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376426   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50376426
PNG
(CHEMBL409545)
Show SMILES CCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cccc(c4)-n4cccn4)ccc3C)c2c1C
Show InChI InChI=1S/C27H26N8O2/c1-4-28-27(37)22-15-35-24(18(22)3)25(29-16-31-35)33-23-14-20(10-9-17(23)2)32-26(36)19-7-5-8-21(13-19)34-12-6-11-30-34/h5-16H,4H2,1-3H3,(H,28,37)(H,32,36)(H,29,31,33)
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n/an/a 123n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of p38alpha

Bioorg Med Chem Lett 18: 2739-44 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.067
BindingDB Entry DOI: 10.7270/Q29887X6
More data for this
Ligand-Target Pair