BDBM50376721 CHEMBL408221

SMILES: Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(cc(Cl)c2o1)C#N

InChI Key: InChIKey=HHWXRJCHILYLEI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376721   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376721 (CHEMBL408221) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(cc(Cl)c2o1)C#N Show InChI InChI=1S/C23H16ClN3O3/c1-14-4-2-3-5-20(14)29-13-21(28)26-17-8-6-16(7-9-17)23-27-19-11-15(12-25)10-18(24)22(19)30-23/h2-11H,13H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50376721 (CHEMBL408221) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(cc(Cl)c2o1)C#N Show InChI InChI=1S/C23H16ClN3O3/c1-14-4-2-3-5-20(14)29-13-21(28)26-17-8-6-16(7-9-17)23-27-19-11-15(12-25)10-18(24)22(19)30-23/h2-11H,13H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair