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BDBM50376799 CHEMBL259754

SMILES: CCN(C1CCCc2nc(cc(OC)c12)-c1cccnc1)c1cccc2ccccc12

InChI Key: InChIKey=HHZIUGCHISUKOA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))		BDBM50376799
PNG
(CHEMBL259754)
Show SMILES CCN(C1CCCc2nc(cc(OC)c12)-c1cccnc1)c1cccc2ccccc12 |w:3.2|
Show InChI InChI=1S/C27H27N3O/c1-3-30(24-14-6-10-19-9-4-5-12-21(19)24)25-15-7-13-22-27(25)26(31-2)17-23(29-22)20-11-8-16-28-18-20/h4-6,8-12,14,16-18,25H,3,7,13,15H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair