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BDBM50376810 CHEMBL260610

SMILES: CCc1cccc(CC)c1-c1cc(CC)c2C(CCCc2n1)N(C)Cc1cccc2ccccc12

InChI Key: InChIKey=SNHDOLGZGJLJPR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))		BDBM50376810
PNG
(CHEMBL260610)
Show SMILES CCc1cccc(CC)c1-c1cc(CC)c2C(CCCc2n1)N(C)Cc1cccc2ccccc12 |w:16.24|
Show InChI InChI=1S/C33H38N2/c1-5-23-14-10-15-24(6-2)32(23)30-21-25(7-3)33-29(34-30)19-12-20-31(33)35(4)22-27-17-11-16-26-13-8-9-18-28(26)27/h8-11,13-18,21,31H,5-7,12,19-20,22H2,1-4H3
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair