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BDBM50376821 CHEMBL259341

SMILES: CCNC1CCCc2nc(cc(OC)c12)-c1c(CC)cccc1CC

InChI Key: InChIKey=LOGDISOWGIAGFG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376821   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))		BDBM50376821
PNG
(CHEMBL259341)
Show SMILES CCNC1CCCc2nc(cc(OC)c12)-c1c(CC)cccc1CC |w:3.2|
Show InChI InChI=1S/C22H30N2O/c1-5-15-10-8-11-16(6-2)21(15)19-14-20(25-4)22-17(23-7-3)12-9-13-18(22)24-19/h8,10-11,14,17,23H,5-7,9,12-13H2,1-4H3
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PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair