BDBM50376826 CHEMBL408460

SMILES: CCN(C1CCCc2nc(cc(OC)c12)-c1ccccc1C)c1cccc2ccccc12

InChI Key: InChIKey=JFOVPHALQDHNQN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50376826 (CHEMBL408460) Show SMILES CCN(C1CCCc2nc(cc(OC)c12)-c1ccccc1C)c1cccc2ccccc12 |w:3.2| Show InChI InChI=1S/C29H30N2O/c1-4-31(26-17-9-13-21-12-6-8-15-23(21)26)27-18-10-16-24-29(27)28(32-3)19-25(30-24)22-14-7-5-11-20(22)2/h5-9,11-15,17,19,27H,4,10,16,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson PRD Curated by ChEMBL					Assay Description Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization				Bioorg Med Chem Lett 18: 2544-8 (2008) Article DOI: 10.1016/j.bmcl.2008.03.049 BindingDB Entry DOI: 10.7270/Q2JM2BHD
					More data for this Ligand-Target Pair