BDBM50377354 CHEMBL265431

SMILES: CSc1nnc(o1)-c1cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c2c1C(C)C

InChI Key: InChIKey=QEVHIVQQGVWVBN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377354 (CHEMBL265431) Show SMILES CSc1nnc(o1)-c1cn2ncnc(Nc3cnc4[nH]c(C)cc4c3)c2c1C(C)C Show InChI InChI=1S/C20H20N8OS/c1-10(2)15-14(19-26-27-20(29-19)30-4)8-28-16(15)18(22-9-23-28)25-13-6-12-5-11(3)24-17(12)21-7-13/h5-10H,1-4H3,(H,21,24)(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair