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SMILES: C[C@@H](O)COc1cn2ncnc(Nc3cnc4[nH]ccc4c3)c2c1C(C)C

InChI Key: InChIKey=UGDNQYIMJCMMJI-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377363   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50377363
PNG
(CHEMBL265191)
Show SMILES C[C@@H](O)COc1cn2ncnc(Nc3cnc4[nH]ccc4c3)c2c1C(C)C
Show InChI InChI=1S/C19H22N6O2/c1-11(2)16-15(27-9-12(3)26)8-25-17(16)19(22-10-23-25)24-14-6-13-4-5-20-18(13)21-7-14/h4-8,10-12,26H,9H2,1-3H3,(H,20,21)(H,22,23,24)/t12-/m1/s1
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n/an/a 165n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human VEGFR2

Bioorg Med Chem Lett 18: 2985-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.057
BindingDB Entry DOI: 10.7270/Q28053HZ
More data for this
Ligand-Target Pair