BDBM50377570 CHEMBL259136

SMILES: CNCc1cnccc1Oc1ccc(Cl)cc1Cl

InChI Key: InChIKey=MPTXQMSURVDICU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50377570 (CHEMBL259136) Show SMILES CNCc1cnccc1Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H12Cl2N2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(14)6-11(13)15/h2-6,8,16H,7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2896-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.082 BindingDB Entry DOI: 10.7270/Q2ZG6T44
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50377570 (CHEMBL259136) Show SMILES CNCc1cnccc1Oc1ccc(Cl)cc1Cl Show InChI InChI=1S/C13H12Cl2N2O/c1-16-7-9-8-17-5-4-12(9)18-13-3-2-10(14)6-11(13)15/h2-6,8,16H,7H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2896-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.082 BindingDB Entry DOI: 10.7270/Q2ZG6T44
					More data for this Ligand-Target Pair