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BDBM50377644 CHEMBL1162978

SMILES: Clc1cnc(NC(=O)c2ccccc2NC(=O)c2ccc(cc2)-n2ccccc2=O)nc1

InChI Key: InChIKey=QHRIPCAEEYTQHW-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50377644   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50377644
PNG
(CHEMBL1162978)
Show SMILES Clc1cnc(NC(=O)c2ccccc2NC(=O)c2ccc(cc2)-n2ccccc2=O)nc1
Show InChI InChI=1S/C23H16ClN5O3/c24-16-13-25-23(26-14-16)28-22(32)18-5-1-2-6-19(18)27-21(31)15-8-10-17(11-9-15)29-12-4-3-7-20(29)30/h1-14H,(H,27,31)(H,25,26,28,32)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 18: 2845-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.092
BindingDB Entry DOI: 10.7270/Q2611169
More data for this
Ligand-Target Pair