Found 4 hits for monomerid = 50377703 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50377703
(CHEMBL258243)Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25| Show InChI InChI=1S/C23H32N2O4S/c1-16-2-3-20(11-21(16)30(27,28)25-4-6-29-7-5-25)22(26)24-15-23-12-17-8-18(13-23)10-19(9-17)14-23/h2-3,11,17-19H,4-10,12-15H2,1H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human cloned CB2 receptor |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50377703
(CHEMBL258243)Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25| Show InChI InChI=1S/C23H32N2O4S/c1-16-2-3-20(11-21(16)30(27,28)25-4-6-29-7-5-25)22(26)24-15-23-12-17-8-18(13-23)10-19(9-17)14-23/h2-3,11,17-19H,4-10,12-15H2,1H3,(H,24,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Displacement of [3H]CP-55940 from human cloned CB1 receptor |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50377703
(CHEMBL258243)Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25| Show InChI InChI=1S/C23H32N2O4S/c1-16-2-3-20(11-21(16)30(27,28)25-4-6-29-7-5-25)22(26)24-15-23-12-17-8-18(13-23)10-19(9-17)14-23/h2-3,11,17-19H,4-10,12-15H2,1H3,(H,24,26) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Agonist activity at human cloned CB1 receptor by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50377703
(CHEMBL258243)Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25| Show InChI InChI=1S/C23H32N2O4S/c1-16-2-3-20(11-21(16)30(27,28)25-4-6-29-7-5-25)22(26)24-15-23-12-17-8-18(13-23)10-19(9-17)14-23/h2-3,11,17-19H,4-10,12-15H2,1H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Agonist activity at human cloned CB2 receptor by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 18: 2830-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.006 BindingDB Entry DOI: 10.7270/Q2P2701M |
More data for this Ligand-Target Pair | |