null

SMILES: COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3s2)CC1

InChI Key: InChIKey=OUNYCNQDFAUREF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50378002 (CHEMBL1627320 | US8748608, 39) Show SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3s2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-21-8-4-3-7-20(21)27-14-12-26(13-15-27)17-19(28)10-11-25-24(29)23-16-18-6-2-5-9-22(18)31-23/h2-9,16,19,28H,10-15,17H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The United States of America as Represented by the Secretary of the Department of Health and Human Services; The University of North Texas Health Science Center at Fort Worth US Patent					Assay Description Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...				US Patent US8748608 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KVC
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50378002 (CHEMBL1627320 | US8748608, 39) Show SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3s2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-21-8-4-3-7-20(21)27-14-12-26(13-15-27)17-19(28)10-11-25-24(29)23-16-18-6-2-5-9-22(18)31-23/h2-9,16,19,28H,10-15,17H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug AbuseIntramural Research Program Curated by ChEMBL					Assay Description Displacement of [125]IABN from human D3 receptor expressed in HEK293 cells				J Med Chem 52: 2559-70 (2009) Article DOI: 10.1021/jm900095y BindingDB Entry DOI: 10.7270/Q2HX1DKJ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50378002 (CHEMBL1627320 | US8748608, 39) Show SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3s2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-21-8-4-3-7-20(21)27-14-12-26(13-15-27)17-19(28)10-11-25-24(29)23-16-18-6-2-5-9-22(18)31-23/h2-9,16,19,28H,10-15,17H2,1H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug AbuseIntramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from D1 receptor				J Med Chem 52: 2559-70 (2009) Article DOI: 10.1021/jm900095y BindingDB Entry DOI: 10.7270/Q2HX1DKJ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50378002 (CHEMBL1627320 | US8748608, 39) Show SMILES COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3s2)CC1 Show InChI InChI=1S/C24H29N3O3S/c1-30-21-8-4-3-7-20(21)27-14-12-26(13-15-27)17-19(28)10-11-25-24(29)23-16-18-6-2-5-9-22(18)31-23/h2-9,16,19,28H,10-15,17H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.1	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug AbuseIntramural Research Program Curated by ChEMBL					Assay Description Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesis				J Med Chem 52: 2559-70 (2009) Article DOI: 10.1021/jm900095y BindingDB Entry DOI: 10.7270/Q2HX1DKJ
					More data for this Ligand-Target Pair