BDBM50378359 CHEMBL575963

SMILES: Cc1cc2nc(-c3ccc(NC(=O)\C=C\c4ccc(F)cc4)cc3)n(O)c2cc1[N+]([O-])=O

InChI Key: InChIKey=PKJBWJRARCOLMO-NYYWCZLTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Exoenzyme S synthesis regulatory protein exsA (Pseudomonas aeruginosa)	BDBM50378359 (CHEMBL575963) Show SMILES Cc1cc2nc(-c3ccc(NC(=O)\C=C\c4ccc(F)cc4)cc3)n(O)c2cc1[N+]([O-])=O Show InChI InChI=1S/C23H17FN4O4/c1-14-12-19-21(13-20(14)28(31)32)27(30)23(26-19)16-5-9-18(10-6-16)25-22(29)11-4-15-2-7-17(24)8-3-15/h2-13,30H,1H3,(H,25,29)/b11-4+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Paratek Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa ExsA binding to DNA				J Med Chem 52: 5626-34 (2009) Article DOI: 10.1021/jm9006577 BindingDB Entry DOI: 10.7270/Q2XD12KZ
					More data for this Ligand-Target Pair