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BDBM50378454 LINDBLADIONE

SMILES: CCCC(=O)CC=C1C(=O)C(=O)c2cc(O)c(O)cc2C1=O

InChI Key: InChIKey=PIMVOTYMDAFECJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50378454   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcription factor HES-1


(Mus musculus)
BDBM50378454
PNG
(LINDBLADIONE)
Show SMILES CCCC(=O)CC=C1C(=O)C(=O)c2cc(O)c(O)cc2C1=O |w:6.5|
Show InChI InChI=1S/C16H14O6/c1-2-3-8(17)4-5-9-14(20)10-6-12(18)13(19)7-11(10)16(22)15(9)21/h5-7,18-19H,2-4H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Chiba University

Curated by ChEMBL


Assay Description
Inhibition of Cy3-labeled mouse recombinant Hes1 (3-281) dimer formation expressed in Escherichia coli by microplate-based assay


Bioorg Med Chem Lett 19: 5778-81 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.146
BindingDB Entry DOI: 10.7270/Q26Q1Z5X
More data for this
Ligand-Target Pair